Mounjaro KwikPen (Tirzepatide) Pre-filled Pen

Mounjaro (tirzepatide) is a once-weekly injection in a pre-filled KwikPen. It acts on two gut hormones, GIP and GLP-1, which help the body control blood sugar, reduce appetite and make you feel full sooner.

Used for

• Adults with type 2 diabetes, to improve blood sugar control, alongside diet and exercise
• Weight management in adults with a BMI of 30 or more, or 27 or more with a weight-related health problem such as high blood pressure, diabetes or sleep apnoea, alongside a reduced-calorie diet and more physical activity

Available in 2.5 mg, 5 mg, 7.5 mg, 10 mg and 15 mg. Each pen holds 4 weekly doses. Made by Eli Lilly.

Prescription medicine. Our doctor reviews your details and medical questionnaire before it is supplied, and may call you to check that it suits you.

• Inject once a week, on the same day each week, at any time of day, with or without food.
• Inject under the skin of the tummy, thigh or upper arm, and change the spot each week.
• Starting dose: 2.5 mg once a week for 4 weeks, then 5 mg. Our doctor may increase the dose in 2.5 mg steps, at least 4 weeks apart, up to 15 mg a week.
• Missed dose: if 4 days or less have passed, inject as soon as you can. If more than 4 days have passed, skip it and inject on your usual day.
• Read the pen instructions in the pack before first use, and use a new pen needle for each injection.

Storage: keep unused pens in the fridge (2 to 8°C). Do not freeze. Follow the pack leaflet for how long a pen can be kept out of the fridge once in use.

Most side effects affect the stomach and gut, and are most common when starting or increasing the dose:

• Nausea, vomiting, diarrhoea or constipation
• Less appetite, indigestion, burping or bloating
• Tiredness
• Redness or itching where you inject
• Low blood sugar, mainly if you also take insulin or a sulfonylurea such as gliclazide

Stop and see a doctor straight away if you get severe stomach pain that does not go away (with or without vomiting), which can be a sign of pancreatitis, pain in the upper right tummy or yellow skin or eyes (gallbladder problems), signs of an allergic reaction, or vomiting or diarrhoea that leaves you dehydrated.

• Do not use if you or a family member has had medullary thyroid cancer, or if you have multiple endocrine neoplasia type 2 (MEN 2). Tell our doctor about a lump or swelling in your neck, trouble swallowing or a hoarse voice.
• Do not use if you are pregnant, trying to become pregnant or breastfeeding.
• If you take the contraceptive pill, it may work less well for 4 weeks after starting and after each dose increase. Use a condom as well during those weeks, or switch to a non-oral method.
• Tell our doctor if you have had pancreatitis, gallbladder disease, severe stomach or gut problems, kidney problems or diabetic eye disease.
• Do not use together with other GLP-1 medicines such as semaglutide or liraglutide.
• Drink enough fluids if you have vomiting or diarrhoea, to avoid dehydration.